Findings

Between Sept 8, 2021, and March 9, 2022, 1443 patients underwent non-AI assisted colonoscopy before (n=795) and after (n=648) the introduction of AI (median age 61 years [IQR 45–70], 847 [58·7%] female, 596 [41·3%] male). The ADR of standard colonoscopy decreased significantly from 28·4% (226 of 795) before to 22·4% (145 of 648) after exposure to AI, corresponding with an absolute difference of –6·0% (95% CI –10·5 to –1·6; p=0·0089). In multivariable logistic regression analysis, exposure to AI (odds ratio 0·69 [95% CI 0·53–0·89]), male versus female patient sex (1·78 [1·38–2·30]), and patient age ≥60 years versus <60 years (3·60 [2·74–4·72]) were the independent factors significantly associated with ADR.